A major development in steam cell science has been achieved with the formation of a two -sided mouse, which is an important step in reproductive biology. Scientists have successfully engineered the mouse with two male biological parents, who have been able to survive in their youth. The research, conducted by a team of steam cell experts, has modified the specific impressions of the genes and resolved the long -standing obstacles in the reproduction of foreign artisans. From the results, which can be the implications of regeneration, highlight the challenges of technology and the potential application of the future.

Genetic modification enables two ancestral growth

According to Study Appeared in the cell stem cell, which headed Chinese Academy of Sciences (CAS), the team focused on overcoming the challenges related to the impression, which prevents the first homosexual genetic starters from fully development. The frame shift was modified, using techniques such as deleting gene, and editing regulatory region. These changes allowed some of the two abstinence to survive until birth and reach youth in extraordinary cases.

Coasal co -respondent writer Qi Chu Specified This impressing genes has been identified as an important obstacle to foreign regeneration. Despite the previous efforts using the ovarian organizations derived from male stem cells, umprating abnormalities leads to severe development defects. By editing these genes directly, the research team improved the stability of fetal and paloripotant stem cells.

Survival and reproductive challenges remain

According to reports, only 11.8 % of the engineers were ready for birth, and those who survived show developmental abnormalities, reduce life and sterilization. Gone Zheng Lou, a joint author, author of Sun Yat Sen.

Despite the limits, this approach has shown the possibility of improving stem cell -based treatment and improving cloning performance. Researchers intend to extend this study to the larger, though many challenges are due to the difference in improving gene patterns in species.

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